[Taxacom] Felsenstein lecture available on-line

Dr. David Campbell amblema at bama.ua.edu
Fri Dec 5 16:19:03 CST 2008

> David Campbell wrote:
> "Aligning or at least checking alignments by hand is a valuable way
> to catch anomalous sequences, whereas feeding raw sequences into an
> analysis that internalizes the homology model makes anomalous
> sequences easy to overlook."
> Are you referring here to POY?

POY is probably the most prominent example of what I was cautioning 
about.  Of course, you can look at the sequences and then feed them 
into POY, or even take a second look at anything that places oddly 
(especially if different genes are giving different results) after you 
run it, but I am aware of a few curious results that came out of POY 
due to bacterial or otherwise anomalous sequences that were supposed to 
be molluscan.  

Dr. David Campbell
425 Scientific Collections Building
Department of Biological Sciences
Biodiversity and Systematics
University of Alabama, Box 870345
Tuscaloosa AL 35487-0345  USA

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