[Taxacom] Primate miRNA

Robin Leech releech at telusplanet.net
Thu Nov 6 14:30:13 CST 2008


A research professor named Renee,
Cloned people from ape DNA.
The project went well,
As anyone can tell,
'Cuz they're all in Parliament today.

Robin

----- Original Message ----- 
From: "Karl Magnacca" <kmagnacca at wesleyan.edu>
To: <TAXACOM at mailman.nhm.ku.edu>
Sent: Thursday, November 06, 2008 12:25 PM
Subject: Re: [Taxacom] Primate miRNA


> 
> On Thu, November 6, 2008 6:38 pm, John Grehan wrote:
>> Zhang et al 2008. Mol Biol Evol 25: 1493-1502. Molecular evolution of a
>> primate-specific microRNA family.
>>
>> p. 1495. "It was shown that mouse, rate, and dog do not have homologs of
>> the miRNAs in this family; therefore, the emergence and rapid expansion
>> of this miRNA family ARE RESTRICTED TO PRIMATES" (emphasis mine). The
>> last bit seems to be stupid because there is nothing to preclude this
>> family being in any other non-primate group. Am I wrong on this?
> 
> Rodents + lagomorphs are sister to primates (with some small groups
> thrown in) and carnivores are part of the group sister to that, so for
> the miRNAs to be ancestral would require two losses, or a loss and a
> gain.  The sentence probably should have been phrased as "likely
> restricted to primates", but it's a reasonable conclusion.
> 
> Karl
> =====================
> Karl Magnacca
> Postdoctoral Researcher
> Department of Zoology
> Trinity College, Dublin 2
> Ireland
> 
> 
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